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Cellular Detoxification

I receive so many inquiries about the cellular detoxification protocols and key nutritional support we utilize with our practice members and clients. Instead of ME trying to re-invent the wheel, I thought it best to simply share the information already provided by our colleague and co-creator of the protocol, Dr. Pompa.

If you have interest in the True Cellular Detoxification protocol, please let me know!

Here’s the overview:

 

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Safe cell detoxification of chemicals and heavy metals is vitally important if you want to achieve healthy cellular function. Years ago, I lost my health, and almost my life, to heavy metal toxicity. I needed to seek out a substance powerful enough to support my body to detoxify mercury, and usher it out of my sick body. However, true heavy metal binders like a clinoptilolite zeolite were far and few between.

 

Supposed natural heavy metal chelators, such as cilantro and chlorella, proved to be too weak to bind to the heavy metals, ultimately allowing these toxins to re-circulate back into the fatty tissue and cells of my body.

These natural binders may show some binding capacity in a glass beaker or lab setting. However, once in the gut, microbial activity typically eliminate and alter these plant based structures, rendering them unable to truly bind to toxins. Therefore, these natural plant chelators are not true binders.

Dimercaptosuccinic acid or DMSA is a true binder, and I did use it successfully back when I was sick. However, accessing a good quality DMSA has become a real challenge (due to recent regulations).

When we realized we no longer had easy access to DMSA, I was faced with some real challenges. I became very concerned for my sick clients.

When you are detoxing heavy metals, you MUST have a true binder that can support the body’s natural ability to detoxify. We did not have a good option for them.

My wife said, “You need to pray about this” One week later I received a call about CytoDetox containing a new clinoptilolite zeolite structure that was the answer to our prayers. Of course, I was skeptical, but when I learned that CytoDetox contains this new clinoptilolite zeolite structure and other natural binders we immediately started the process of clinical application and discovery. Therefore, we tested it with both our laboratories and our large health practitioner network.  The results are in!

For over 3 years now, our practitioner network has utilized CytoDetox for cell detoxification support with amazing analytical test results and health testimonials. Now, with the new and improved CytoDetox, we expect even more amazing results, testimonies and gratitude to pour into our inboxes.

My goal here is to help you understand the science of CytoDetox, so you can skyrocket your cell detoxification routine today. CytoDetox is a tool our practitioners find critical to supporting their clients health outcomes, and we want to share this breakthrough science and discovery with you.

Clinoptilolite Zeolite Structure Holds Tight for Cell Detoxification Support

CytoDetox has created a groundbreaking change in supporting our body’s natural cell detoxification systems. I challenged its efficacy at first. Many people have introduced liquid zeolites, clinoptilolite zeolite, and other zeolite structures to me. The problem being that these liquid zeolites only contained particles which are supportive to the body, with one caveat. Based upon the size of the particle, they stay in the gut and cannot pass cellular membranes. As a result, none of these other products proved to be effective.

My other challenge after losing DMSA, was that most other binders available couldn’t keep a strong hold on heavy metals. Because these other products couldn’t fully bind, the metals were not completely eliminated, and therefore ended up re-circulating back into the body. The clinoptilolite zeolite found in CytoDetox® can fully bind and hold heavy metals and other toxins tightly, therefore, re-distribution in the body is no longer a valid concern¹.

The Origin Story of CytoDetox You Need to Know

I want everyone to understand the science behind CytoDetox, as it differentiates itself from all other zeolites and cell detoxification support products.

CytoDetox is derived from a special type (1 of 40) of zeolites called clinoptilolite^2,3.

From a ‘birds-eye’ perspective, this natural mineral, clinoptilolite, formed millions of years ago from a chemical reaction between volcanic ash and saline water. It can take up to 50,000 years to complete this reaction⁴. Once complete, a unique three-dimensional cage like configuration is created, similar to a honeycomb, which has a natural negative charge. This natural structure acts like a sieve for toxins in the environment^5,6,7.

The clinoptilolite crystal structure is built from Aluminum, Silica and Oxygen creating a very stable and resistant molecule that can attract, exchange, and retain heavy metals and other positively charged toxic molecules.

Commercially, the zeolite structure functions as an effective tool for cationic exchange and absorption of heavy metals such as Uranium, Lead, and Mercury. They have a long history of use in many water filtration systems available both commercially and publically. In fact, for human use, the FDA considers zeolites to be GRAS (Generally Regarded As Safe) as a food additive⁸.

The challenges with zeolite crystals is two-fold:

1. They naturally contain high levels of heavy metals making it difficult to use higher and more effective quantities in formulas.
2. They are large insoluble cage molecules that would not cross the intestinal barriers or membranes.

Heavy Metal Contamination Free Purified Clinoptilolite Zeolite

Natural clinoptilolite zeolite is difficult to use in human systems because, when not cleaned, it naturally contains high level of heavy metals and other contaminants, therefore it has to be diluted significantly before consumption. This limits its overall effectiveness, efficacy and work against supporting cell detoxification.

Using a patent pending process, the natural clinoptilolite zeolite in CytoDetox is stripped of the bound heavy metals, leaving cleaned and prepped cages ready for binding new heavy metals. This purified clinoptilolite zeolite can be used at higher concentrations making it much more effective. Because it has more cleaned cages, it is capable of binding to a higher capacity, heavy metals, and larger toxic molecules.

Molecule Clinoptilolite Fragment Found in CytoDetox

When zeolite is added to water and stirred, a suspension is created. But, as noted, most other zeolite suspensions cannot be absorbed, and have a limited bioavailability in the human gastrointestinal system.

Therefore, any zeolite products that were made before the technology existed to create CytoDetox® were either powdered zeolites or liquid suspensions of zeolites, and absorption was a concern.

CytoDetox contains water-soluble molecular clinoptilolite fragments, as well as some larger insoluble particles with cleaned cages. This is what differentiates it from other zeolite products. Simply, it was designed to support the whole body not just the gut.

In order to transform the zeolite structure or crystal into a water-soluble crystalline molecule, the zeolite structure needs to be broken down into the correct size and molecular weight.

During the process of creating the product, the challenge became breaking the crystal and creating molecular clinoptiloite fragments, while simultaneously making sure to preserve the cage-like structures necessary to maintain the ability to bind heavy metals and other toxins.

After thorough testing, the water soluble molecular clinoptilolite fragments found in solution are the correct size and molecular weight necessary to maintain cage like zeolite structure(s). The fingerprint of the molecular clinoptilolite fragments was confirmed by liquid chromatography and mass spectrometry (LC-MS) to range between 200 and 2000 daltons (more than 10 times the molecular weight that is able to cross a cells mitochondrial membrane).

Testing for the Safety of CytoDetox

Every batch of CytoDetox is tested with a full microbiological testing, according to strict industry requirements. Moreover, the lab operates according to the FDA, cGMP or GLP (good laboratory practices). The testing methodology used is United States Pharmacopeia (USP)/Bacterilogical Analytical Manual (BAM) and Association of Analytical Chemists (AOAC) methodologies.

Our purified CytoDetox® test results for heavy metals, and microorganisms surpass all specifications even at higher clinical concentrations.

Also noteworthy: clinoptilolite zeolite particles contain sodium aluminosilicate, which means their chemical makeup is aluminum, silica and oxygen. This may create the thought that ‘free aluminum’ could enter the body. However, the lab process and analytical analysis suggests that when they broke the crystals, there were no detectable levels of free aluminum in the finished product.

What about our zeolite cages that contain aluminum in the structure?

The soluble molecular clinoptilolite fragments and insoluble clinoptilolite particles are not ‘free aluminum’, rather, these are inert parts of the zeolite structure. This structure is very difficult to break, even in a laboratory setting with strong and caustic chemicals.

Clinoptilolite zeolite can also withstand extremely high temperatures (>1000 ℉), and is not dissolved or broken down by gastric or stomach acids. Therefore, the molecular clinoptilolite fragments and particles can pass through the body completely intact.

As the clinoptilolite zeolite particles and water soluble fragments move through the body, they can easily and safely support the body’s natural ability to detoxify, when they are activated and cleansed of their existing metals.

Crossing Through Cellular Membranes

The real proof of a true cellular binder’s efficacy is whether it can successfully cross cellular membranes as well as the blood brain barrier. To have confidence in a binder, it needs to perform in specific tests that can confirm its ability to travel through cellular membranes unimpeded.

To support CytoDetox’s ability to cross cellular membranes, we must return to biology class, and review how a compound crosses cell membranes. Cell membranes are semi-permeable barriers and gatekeepers to the cell. This means that some molecules can diffuse across the lipid bilayer quickly, slowly, or not all all depending on several factors like charge and size.

Pharmaceutical companies developed the science of liposomes to help deliver drugs into the lymph, blood and targeted tissues through the cells lipid bilayer. We adopted this same science to create the first and only clinoptilolite zeolite liposomes.

Using CytoDetox’s® patent pending liposomal technology we can support the delivery of clinoptilolite molecules beyond cellular barriers.

Why Size Matters in Clinoptilolite Zeolite Structure(s)

CytoDetox contains clinoptilolite that range in molecular size (not weight) from approximately 1 to over 1000 nanometers. This produces various sizes and clusters of cage structures that have the ability to bind larger quantities of toxins in different body systems.

When it comes to cellular membranes, studies show molecular weight, not the measured size is what matters to the cells. The molecular weight (measured in daltons), is what defines a molecules ability to cross into cells and cellular membranes.

LC-MS testing confirmed that the molecular weight of the water soluble clinoptilolite fragments present in CytoDetox are in the range (200 and 2000 daltons) necessary to cross cellular membranes.

Also, insoluble (not water soluble) clinoptilolite particles that are too large to enter cellular membranes, where also added to CytoDetox’s liposomal solution.

These larger clinoptilolite particles were added to further support the body’s natural ability to detoxify other body systems, such as the blood, lymph and gut.

 In addition, we have taken a proven delivery system called liposomal technology to support the transport of clinoptilolite zeolite molecules across cellular membranes.

The creation of clinoptilolite zeolite liposomes further supports the delivery of clinoptilolite molecules (varying molecular weights, sizes, and concentrations) into the lymphatic system, thus providing increased access to blood, cells and tissues.

Even smaller clinoptilolite zeolite molecules may encounter barriers like intestinal tight junctions or membranes, therefore, liposomes increase the efficacy and molecular concentration of every dose.

Liposomes fuse with membranes, and then can release contents into the cell. The liposomes present in CytoDetox are small and stable ranging in size from approximately 20 to 250 nanometers.

We measure the molecular clinoptilolite fragments to verify the dalton size required for inclusion into the liposomal matrix.

Increased Binding Mechanism and Capacity with Fulvates

To support the amazing discovery of molecular clinoptilolite fragments the inventors combined a natural organic acid called fulvates to the CytoDetox formula. In the natural environment, the combination of organic acids like fulvates with zeolites increased heavy metal uptake and binding capacity¹⁰.

Fulvates contain over 33 types of organic acids, amino acids and trace minerals all of which can be beneficial to our cells. Similar to clinoptilolite fragments, fulvates are fragments derived from humates. Fulvates have increased solubility and lower molecular weight while retaining phenolic carboxylic acid groups. Therefore, fulvic acids can bind metals through a true chelation process. Also, research indicates that fulvates are a natural redox molecule with antioxidant capacity and may neutralize harmful free radical toxins in the body¹¹.

The processes in which fulvates are believed to eliminate toxins is complex. The redox potential provides the capacity to carry an electron charge that counteracts the detrimental effects of charged free radicals, or directly as a chelator fulvates use the negatively charged oxygens to trap positively charged minerals like heavy metals.

In sum, fulvates can serve multiple roles within the human body systems to support cell detoxification and cell function. As an electron donor and acceptor, fulvates can provide redox potential-a life force energy.  As complex organic molecules fulvates deliver microbiome nourishment, trace minerals and other nutrients to the body¹².

Going Upstream to the Toxin Source

When looking at upstream toxins (such as heavy metals and environmental chemicals embedded in most of our organs, glands, cells and brain tissue), we know it is of utmost importance to deal with high toxicity in a timely and safe manner.

Unfortunately, you can’t just do a liver or kidney cleanse once a year and think that you are fully cleansed. It is impossible to single out an organ and limit cell detoxification to one part of the body. Even if we were able to select toxins from the liver one at a time, we could only remove an estimated 2% or 3% of the toxic load.

Toxins pass through the liver to be removed, but often end up deposited in fatty tissue and other body tissues, including the brain. What we can do is take CytoDetox to support the body’s natural ability to pass toxins through the liver, and usher them out of the system for complete cell detoxification support.

Note, CytoDetox does not limit itself to supporting removal of heavy metals such as mercury, lead, cadmium and arsenic. CytoDetox can fully support the body for a wide variety of positively charged toxic exposures.

 

 

 

 

CytoDetox and True Cell Detoxification

What is cell detoxification? Unfortunately, in the world of detoxification, instead of concentrating on the upstream toxins, most are focusing on downstream detox methods, such as colonics, juice fasts and the like. These strategies are great as detox support tools, but just not good enough when you are dealing with major health challenges driven by toxins. These cleanses can open up the elimination pathways, and that is beneficial. However, we must get into the cell to effectively clear the debris that is blocking our best cellular health.

 

 

 

One Detox Phase at a Time

Keeping the 5Rs in mind, we created a complete detoxification system using CytoDetox called the True Cellular Detox™ Program which involves 3 phases.

The first step, called the PREP PHASE: Prepares the body and brain for cleansing, supports optimal liver and kidney function, provides high-potency probiotics, and supports cellular purification.

The second step, called the BODY PHASE: Assists in preparing the body for purification of the brain, assists healthy liver enterohepatic circulation cycle cleansing (the circulation of bile salts and other secretions from the liver to the intestine, where they are reabsorbed into the blood and returned to the liver), supports normal methylation processes, and supports normal mitochondria function for optimal cellular energy¹³.

The third step, called the BRAIN PHASE: Assists in purifying the brain, supports safe elimination of impurities, supports normal brain function, and provides intracellular (inside the cell) and neuronal (nerve) antioxidant support.

In a toxic world, I feel blessed that CytoDetox is playing an important role in supporting the body’s natural ability to clear toxins out, that may be robbing our health and quality of life.

With both CytoDetox and the True Cellular Detox™ program, we have extraordinary clinical results, and game-changing tools to boost life-long cellular health, cell detoxification and cell vitality.

 

 

 

• 1. Flowers, James L., Stewart A. Lonky, and Erik J. Deitsch. “Clinical Evidence Supporting the Use of an Activated Clinoptilolite Su | NDS.” Open Access Journal of Sports Medicine. November 04, 2009. https://www.dovepress.com/clinical-evidence-supporting-the-use-of-an-activated-clinoptilolite-su-peer-reviewed-article-NDS.

• 2. “The Mineral Clinoptilolite.” Amethyst Galleries’ Mineral Gallery. http://www.galleries.com/Clinoptilolite.

• 3. “Zeolite.” Wikipedia. https://en.wikipedia.org/wiki/Zeolite.

• 4. “Zeolites”. 1996. Cool.Conservation-Us.Org. http://cool.conservation-us.org/byorg/abbey/an/an20/an20-7/an20-702.html.

• 5. Graves, P.R. Jr. “Process for Fixing Lead-contaminated Ecologically Hazardous Industrial Waste Materials Using Clinoptilolite Zeolite.” AGRIS: International Information System for the Agricultural Science and Technology. January 01, 1996. http://agris.fao.org/agris-search/search.do?recordID=PH9611101.

• 6. Romero, Cecily. “Zeolite Membranes for Removal of Contaminants in Drinking Water.” EPA.https://cfpub.epa.gov/ncer_abstracts/index.cfm/fuseaction/display.highlight/abstract/1173.

• 7. Erdem, E., N. Karapinar, and R. Donat. “The Removal of Heavy Metal Cations by Natural Zeolites.” Egyptian Journal of Medical Human Genetics. September 25, 2004. https://www.sciencedirect.com/science/article/pii/S0021979704007416.

• 8. Center for Food Safety and Applied Nutrition. “Generally Recognized as Safe (GRAS).” U S Food and Drug Administration Home Page.https://www.fda.gov/Food/IngredientsPackagingLabeling/GRAS/.

• 9. Diale, P.P., S.S.L. Mkhize, E. Muzenda, and J. Zimba. The Sequestration of Heavy Metals Contaminating the Wonderfonteinspruit Catchment Area Using Natural Zeolite. PDF. World Academy of Science, Engineering and Technology International Journal of Materials and Metallurgical Engineering, 2011.

• 11. Van, C. E. “The Antiinflammatory Properties of Humic Substances: A Mini Review.” Phytotherapy Research : PTR. June 2015.https://www.ncbi.nlm.nih.gov/pubmed/25732236.

• 12. Swidsinski, A., Y. Dörffel, V. Loening-Baucke, C. Gille, A. Reißhauer, O. Göktas, M. Krüger, J. Neuhaus, and W. Schrödl. “Impact of Humic Acids on the Colonic Microbiome in Healthy Volunteers.” World Journal of Gastroenterology. February 07, 2017. https://www.ncbi.nlm.nih.gov/pubmed/28223733/?i=183&from=humic acid.

• 13. Dogliotti, Giada, Alexis E. Malavazos, Sonia Giacometti, Umberto Solimene, Mauro Fanelli, Massimiliano M. Corsi, and Elena Dozio. Journal of Clinical Biochemistry and Nutrition. May 2012. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334371/.

 

 

Dr. Colleen Trombley-VanHoogstraat (“Dr Mom Online”) is a popular personality in Natural Health & Wellness and is in her 24th year of active practice in Michigan, along with her husband Dr. Marc VanHoogstraat. She’s also the proud mom of two rather fabulous kiddos that she currently home schools. Her unique perspective of the science of Wellness provides predictable solutions and transformational results for those struggling with chronic health issues, as well as those seeking lifelong health. To discover her simple strategies for creating better health through nutrition, movement, mindset, cellular detoxification, and metabolic re-setting, jump on board as a regular reader of Dr Mom Online when you plug in your name and email address.

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